CAS No.1113-41-3|L-Penicillamine
Name:L-Penicillamine CAS No.1113-41-3 EINECS:214-203-9 MF:C5H11NO2S MW:149.21 Purity:95% Package: 1g,5g,25g,100g,500g,1kg,5kg Worldwide Delivery
Categories：
Pharmaceutical Intermediates
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Product introduction
Introduction and application of CAS No. 1113-41-3 | L-Penicillamine
Synonyms:3-THIOL-VALINE;TIMTEC-BB SBB000102;
L-BETA,BETA-DIMETHYLCYSTEINE;
L-BETA-MERCAPTOVALINE;L-(+)-PENICILLAMINE;
L-PENICILLAMINE;
L(+)-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID;
H-BETA,BETA-DIMETHYL-CYS-OH
Specification:
|
ITEMS |
SPECIFICATION |
|
CAS |
1113-41-3 |
|
MF |
C5H11NO2S |
|
MW |
149.21 |
|
Melting point |
206 °C |
|
Boiling point |
251.8±35.0 °C |
|
Density |
1.2±0.1 g/cm3 |
|
Acidity coefficient |
2.13±0.12 |
|
Color |
White to almost white |
|
Solubility |
Soluble in water base (a little), DMSO (slightly, heat), water (slightly) |
|
Form |
crystalline powder |
Introduction:
L-Penicillamine is an intermediate of a specific drug, used to synthesize HIV-1 protease inhibitors. It has strong antiviral ability and has obvious preventive and therapeutic effects on AIDS. It can be seen from the structure that L-penicillamine is an amino acid compound and contains an active carbon atom.
Application:
L-penicillamine is a key intermediate for many drugs and has broad market prospects, such as the synthesis of anti-AIDS protease inhibitors (JE-1520, JE-2147). Both of these drugs are currently in clinical trials and have good potential. It has antiviral efficacy and is also an important intermediate for the treatment of cardiovascular drugs SD3321 and anti-cancer drug AG3340.
Preparation:
penicillamine is used as raw material and acetyl chloride is used as acylating agent. Racemic acetyl-D and L-penicillamine are obtained through acylation with a yield of 74.6%. Acetyl-D, L-penicillamine was hydrolyzed in hydrochloric acid to obtain racemic D, L-penicillamine, with a yield of 76.2%.
Package and transportation :
Package: 1g,5g,25g,100g,500g,1kg,5kg
Transportation: by courier/ by air/ by sea
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